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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 43.64
Human Site: S443 Identified Species: 60
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S443 A T A N D V P S P Y E V R G F
Chimpanzee Pan troglodytes XP_001159528 485 54945 S423 A T A N D V P S P Y E V R G F
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 S418 A T A N D V P S P Y E V R G F
Dog Lupus familis XP_535453 687 75990 S625 A T A N D V P S P Y E V R G F
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 S443 A T A N D V P S P Y E V K G F
Rat Rattus norvegicus P11598 505 56605 S443 A T A N D V P S P Y E V K G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 S420 A T A N D V P S P Y E V R G F
Chicken Gallus gallus Q8JG64 505 56163 S441 A T A N D V P S P Y E V R G F
Frog Xenopus laevis NP_001080051 502 56103 P440 A T A N D V P P Q Y E V R G F
Zebra Danio Brachydanio rerio NP_998070 488 54656 P434 A T A N D V P P N Y D V Q G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 S434 S T A N E L E S I K I S S F P
Honey Bee Apis mellifera XP_623282 490 55838 G428 A T A N D V P G P Y E V R G F
Nematode Worm Caenorhab. elegans P34329 618 69779 S567 A T I N D A P S Q F A V E G F
Sea Urchin Strong. purpuratus XP_782981 472 51996 P418 A T A N D V P P A F E V R G F
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 S445 A T A N D V P S E F D V Q G Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 S439 A T A N D I P S D T F D V K G
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 R443 D H T E N D V R G V V I E G Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 100 86.6 73.3 N.A. 26.6 93.3 60 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 86.6 86.6 N.A. 46.6 93.3 66.6 86.6
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 66.6 N.A. 46.6 6.6 N.A.
P-Site Similarity: N.A. 93.3 N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 89 0 89 0 0 6 0 0 6 0 6 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 89 6 0 0 6 0 12 6 0 0 0 % D
% Glu: 0 0 0 6 6 0 6 0 6 0 65 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 18 6 0 0 6 77 % F
% Gly: 0 0 0 0 0 0 0 6 6 0 0 0 0 89 6 % G
% His: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 6 0 0 6 0 0 6 0 6 6 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 6 0 0 12 6 0 % K
% Leu: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 95 6 0 0 0 6 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 89 18 53 0 0 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 0 0 6 0 0 0 0 53 0 0 % R
% Ser: 6 0 0 0 0 0 0 71 0 0 0 6 6 0 0 % S
% Thr: 0 95 6 0 0 0 0 0 0 6 0 0 0 0 0 % T
% Val: 0 0 0 0 0 77 6 0 0 6 6 83 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 65 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _